abstract：:In order to evaluate the use of the post-tetanic count (PTC) method during repetitive administration of vecuronium, we studied 20 patients allocated randomly to one of two groups: 10 patients received droperidol-fentanyl anaesthesia (control group); 10 other patients were given droperidol-fentanyl anaesthesia modified...

journal_title：British journal of anaesthesia

authors： Eriksson LI,Lennmarken C,Staun P,Viby-Mogensen J

更新日期：1990-10-01 00:00:00

abstract：:The influence of halothane was studied on train-of-four fade during spontaneous recovery from neuromuscular block produced by atracurium in 42 children undergoing routine surgical procedures under general anaesthesia. The ulnar nerve was stimulated at the wrist, and compound electromyographic responses were recorded f...

journal_title：British journal of anaesthesia

authors： Woloszczuk-Gebicka B

更新日期：1990-10-01 00:00:00

abstract：:We have investigated the value of lower oesophageal contractility (LOC) in detecting awareness during anaesthesia in 20 human volunteer patients. LOC was measured either with subjects awake or after induction with propofol, during induction with propofol, and then as consciousness returned. Statistically significant c...

journal_title：British journal of anaesthesia

authors： Isaac PA,Rosen M

更新日期：1990-09-01 00:00:00

abstract：:We have measured the onset and extent of the miotic effect of morphine and alfentanil in conscious patients. Forty unpremedicated ASA I and II patients were allocated randomly to four groups to receive either i.v. saline (control group), morphine 0.1 mg kg-1, alfentanil 4.0 micrograms kg-1 or a combination of these do...

journal_title：British journal of anaesthesia

authors： Miller CD,Asbury AJ,Brown JH

更新日期：1990-09-01 00:00:00

abstract：:We determined in 51 healthy patients undergoing body surface surgery the dose requirements for propofol, as part of a total i.v. anaesthesia technique with an alfentanil infusion. After premedication with temazepam, patients received alfentanil 50 micrograms kg-1 followed by an infusion of 50 micrograms kg-1 h-1. Pati...

journal_title：British journal of anaesthesia

authors： Richards MJ,Skues MA,Jarvis AP,Prys-Roberts C

更新日期：1990-08-01 00:00:00

abstract：:In obstetric patients undergoing postpartum tubal ligation, we found that metoclopramide produced dose-dependent prolongation of suxamethonium-induced neuromuscular block. Mean block times after suxamethonium 1 mg kg-1 were 8.0 min, 9.83 min and 12.45 min for control and metoclopramide 10 mg and metoclopramide 20 mg g...

journal_title：British journal of anaesthesia

authors： Kao YJ,Tellez J,Turner DR

更新日期：1990-08-01 00:00:00

abstract：:Successful tracheal intubation with the flexible fibreoptic bronchoscope requires a certain amount of skill which is acquired by practice. It has been suggested that the new Bullard laryngoscope may be mastered more easily. To determine if learning was superior with a flexible fibreoptic or the Bullard device, the eas...

journal_title：British journal of anaesthesia

authors： Dyson A,Harris J,Bhatia K

更新日期：1990-08-01 00:00:00

abstract：:Bupivacaine 2.5 mg kg-1 (0.5 ml kg-1 of 0.5% solution), with or without adrenaline 5 micrograms ml-1, was administered by interpleural injection to 12 patients after elective cholecystectomy. Noncompartmental analysis indicated that the addition of adrenaline had no effect on total body clearance, apparent volume of d...

journal_title：British journal of anaesthesia

authors： Gin T,Chan K,Kan AF,Gregory MA,Wong YC,Oh TE

更新日期：1990-06-01 00:00:00

abstract：:All 484 candidates for the 1988 Fellowship in Anaesthesia (Part Three) were surveyed to investigate any differences between successful and unsuccessful candidates in study techniques, work and domestic factors, and examination history that might lead to better guidance to those preparing for the examination and an imp...

journal_title：British journal of anaesthesia

authors： David AC,Elton RA,Spence AA,Hatch DJ

更新日期：1990-06-01 00:00:00

abstract：:A retrospective study of serious non-fatal complications of extradural block in obstetric practice was carried out using a postal questionnaire. Two hundred and three obstetric units in the United Kingdom (responsible for 2,580,000 deliveries from 1982 to 1986 inclusive) responded. A total of 505,000 extradural blocks...

journal_title：British journal of anaesthesia

authors： Scott DB,Hibbard BM

更新日期：1990-05-01 00:00:00

abstract：:A retrospective study was carried out to determine analgesic requirements in a group of orthopaedic outpatients (n = 145) and oral surgery inpatients (n = 172). The orthopaedic patients received a codeine-paracetamol premedication, an opioid during operation, or no analgesic. Less than 50% of the orthopaedic patients ...

journal_title：British journal of anaesthesia

authors： Campbell WI

更新日期：1990-05-01 00:00:00

abstract：:We have studied the relationship between gas exchange and mechanical frequency response during high frequency jet ventilation (HFJV) at 0.5-5.0 Hz in anaesthetized pigs. The mechanical gain curve showed a minimal "anti-resonant" response at 0.8 Hz (f1) and a maximal "resonant" response at 5.0 Hz (f2). This finding may...

journal_title：British journal of anaesthesia

authors： Lin ES,Jones MJ,Mottram SD,Smith BE,Smith G

更新日期：1990-04-01 00:00:00

abstract：:The neuromuscular blocking effects of Org 9426, the 2-morpholino, 16-allyl-pyrrolidino derivative of the 3-desacetoxy analogue of vecuronium have been investigated in anaesthetized patients. Based on data from a pilot study, two doses, 250 and 500 micrograms kg-1 (estimated as the ED90 and 2 x ED90, respectively) were...

journal_title：British journal of anaesthesia

authors： Wierda JM,de Wit AP,Kuizenga K,Agoston S

更新日期：1990-04-01 00:00:00

abstract：:An oxygen consuming lung model was used for evaluation and validation of a technique for metabolic gas exchange measurements during controlled ventilation. The technique comprised a Servo 900 C ventilator (Siemens) and separate oxygen and carbon dioxide analysers (Beckman). Measurements of oxygen consumption and carbo...

journal_title：British journal of anaesthesia

authors： Svensson KL,Sonander HG,Stenqvist O

更新日期：1990-03-01 00:00:00

abstract：:Forty patients (age range 60-79 yr) undergoing transurethral surgery were allocated randomly to receive 0.5% plain bupivacaine 4 ml at the L2-3 (n = 20) or L4-5 (n = 20) space. The solution was injected over 30 s with the patient in the sitting position. The patient was kept sitting for 2 min, then placed supine and, ...

journal_title：British journal of anaesthesia

authors： Olsen KH,Nielsen TH,Kristoffersen E,Husegaard HC,Wernberg M,Dørup J

更新日期：1990-02-01 00:00:00

abstract：:Seventy-two adult surgical patients were studied to compare neuromuscular and cardiovascular effects of mivacurium chloride during nitrous oxide-fentanyl-thiopentone (BAL group) or nitrous oxide-halothane (HAL group) anaesthesia. Eighteen patients in the BAL group received an initial bolus of mivacurium, either the ED...

journal_title：British journal of anaesthesia

authors： From RP,Pearson KS,Choi WW,Abou-Donia M,Sokoll MD

更新日期：1990-02-01 00:00:00

abstract：:A computer-controlled infusion of propofol designed to achieve a target blood concentration of propofol 3 microgram ml-1 was used to investigate the possibility of an interaction between propofol and fentanyl in 32 patients undergoing body surface surgery. In 16 patients who were not receiving a neuromuscular blocker ...

journal_title：British journal of anaesthesia

authors： Dixon J,Roberts FL,Tackley RM,Lewis GT,Connell H,Prys-Roberts C

更新日期：1990-02-01 00:00:00

abstract：:We describe a scavenging device, primarily for use during inhalation induction of anaesthesia in children; it was designed to optimize the often conflicting requirements of clinical acceptability and adequate gas collection. The performance was assessed in three ways. The device reduced the nitrous oxide concentration...

journal_title：British journal of anaesthesia

authors： Sik MJ,Lewis RB,Eveleigh DJ

更新日期：1990-01-01 00:00:00

abstract：:We have compared the effects of the anaesthetic gases nitrogen and argon on adenosine diphosphate (ADP)-induced human blood platelet aggregation with the effects of the non-anaesthetic gas helium. All three gases showed dose-dependent inhibition of platelet aggregation. For nitrogen and argon there was a linear relati...

journal_title：British journal of anaesthesia

authors： McIver DJ,Fields ND,Philp RB

更新日期：1990-01-01 00:00:00

abstract：:We have measured in a double-blind study the changes in intraocular pressure (IOP) in 40 consecutive patients (pretreated with fentanyl or alfentanil) who received suxamethonium and tracheal intubation. Although IOP increased significantly following administration of suxamethonium, mean IOP in both groups remained sig...

journal_title：British journal of anaesthesia

authors： Sweeney J,Underhill S,Dowd T,Mostafa SM

更新日期：1989-12-01 00:00:00

abstract：:The effects of doxacurium chloride, a new long-acting non-depolarizing neuromuscular blocking drug, on cardiac performance were studied in 45 patients undergoing high-dose fentanyl-diazepam-oxygen anaesthesia for cardiac surgery. Data were collected at baseline (10 min after tracheal intubation), and at 2, 5 and 10 mi...

journal_title：British journal of anaesthesia

authors： Reich DL,Konstadt SN,Thys DM,Hillel Z,Raymond R,Kaplan JA

更新日期：1989-12-01 00:00:00

abstract：:Gastric pH and volume were measured in 87 patients who had received i.v. omeprazole (a new gastric antisecretory agent) 40 mg or placebo 1 or 3 h before surgery. Omeprazole increased the pH of gastric contents in the majority of patients. Administration 1 h before surgery produced greater gastric pH and smaller volume...

journal_title：British journal of anaesthesia

authors： Cruickshank RH,Morrison DA,Bamber PA,Nimmo WS

更新日期：1989-11-01 00:00:00

abstract：:A 55-yr-old man received a left supraclavicular brachial plexus block with 0.42% bupivacaine; he had profound motor and sensory block 26 h after injection; complete recovery occurred at 40 h. ...

journal_title：British journal of anaesthesia

authors： Brockway MS,Winter AW,Wildsmith JA

更新日期：1989-11-01 00:00:00

abstract：:The pressor and catecholamine responses to laryngoscopy and intubation were studied in nine patients with pregnancy-induced hypertension (PIH) and in eight normotensive controls. Five of the PIH patients had received oral labetalol as antihypertensive therapy. Mean arterial pressure (MAP) increased significantly from ...

journal_title：British journal of anaesthesia

authors： Lavies NG,Meiklejohn BH,May AE,Achola KJ,Fell D

更新日期：1989-10-01 00:00:00

abstract：:The serum vasopressin (S-AVP) concentration, serum sodium concentration and osmolality, central venous pressure and fluid balance were measured during 10-min periods in 32 patients undergoing transurethral resection of the prostate. Concentration of S-AVP was unaffected by uncomplicated resection; irrigant absorption ...

journal_title：British journal of anaesthesia

authors： Hahn RG,Rundgren M

更新日期：1989-09-01 00:00:00

abstract：:This study was designed to investigate if propofol produced cardiovascular effects by direct actions or by indirect actions secondary to depression of the central nervous system. Experiments were performed on chloralose anaesthetized dogs in which all neurogenic cardiovascular reflexes were abolished by bilateral vago...

journal_title：British journal of anaesthesia

authors： Goodchild CS,Serrao JM

更新日期：1989-07-01 00:00:00

abstract：:Single dose-response curves were determined for suxamethonium in neonates, infants and children during thiopentone-fentanyl-nitrous oxide anaesthesia. During onset of neuromuscular block, suxamethonium produced an increase in muscle tone which was greatest in neonates and infants. The dose-response curves for the thre...

journal_title：British journal of anaesthesia

authors： Meakin G,McKiernan EP,Morris P,Baker RD

更新日期：1989-06-01 00:00:00

abstract：:We evaluated the use of an inexpensive trans-illuminating light wand for tracheal intubation. Expertise in its use was acquired quickly, thereby providing successful per-oral intubation in all patients who were able to open the mouth, irrespective of the view obtained of the epiglottis and larynx. ...

journal_title：British journal of anaesthesia

authors： Ainsworth QP,Howells TH

更新日期：1989-05-01 00:00:00

abstract：:Diltiazem inhibited and antagonized the abnormal contractures induced by halothane, caffeine and potassium chloride in isolated skeletal muscle from pigs susceptible to malignant hyperpyrexia (MHS). Contractile responses to caffeine and electrical stimulation also were suppressed by diltiazem in control tissue. Simila...

journal_title：British journal of anaesthesia

authors： Foster PS,Denborough MA

更新日期：1989-05-01 00:00:00

abstract：:We have investigated, in six healthy male volunteers, the effect of high thoracic extradural anaesthesia on the ventilatory pattern and hypercapnic ventilatory response. Ventilatory variables were determined using a respiratory inductive plethysmograph. Duration of inspiration, rib cage excursion and its contribution ...

journal_title：British journal of anaesthesia

authors： Kochi T,Sako S,Nishino T,Mizuguchi T

更新日期：1989-04-01 00:00:00

abstract：:We studied the interaction between paracetamol (acetaminophen U.S.P.) and enflurane. Sixteen rats were assigned to four groups (n = 4) to receive: paracetamol 7.5 mg/100 g body weight; paracetamol plus 1% enflurane; 1% enflurane alone, or no treatment (controls). Animals were killed 6 h later. A second series of 16 we...

journal_title：British journal of anaesthesia

authors： Hanna AN,McDonald JS,Miller CH Jr,Couri D

更新日期：1989-04-01 00:00:00

abstract：:We present a new pattern of nerve stimulation--double burst stimulation (DBS)--to detect residual neuromuscular block manually. The DBS consists of two short lasting, 50-Hz tetanic stimuli or bursts separated by a 750-ms interval. The response to this pattern of stimulation is two single separated muscle contractions ...

journal_title：British journal of anaesthesia

authors： Engbaek J,Ostergaard D,Viby-Mogensen J

更新日期：1989-03-01 00:00:00

abstract：:A double-blind crossover volunteer trial has been carried out to determine if oral doxapram reduces the respiratory depression caused by morphine 0.12 mg kg-1 i.m. Doxapram was given to the subjects 90 min before the morphine and significantly reduced the displacement of the ventilatory response to carbon dioxide caus...

journal_title：British journal of anaesthesia

authors： Randall NP,Pleuvry BJ,Fazackerley EJ,Modla CY,Prescott LF,Healy TE

更新日期：1989-02-01 00:00:00

abstract：:The effect of diluting propofol in 5% dextrose on the incidence of i.v. injection pain was studied in 100 adult patients. Severe injection pain occurred in 32% (16 patients) who received undiluted propofol, compared with 10% (five patients) who received dilute propofol. We concluded that the dilution of propofol signi...

journal_title：British journal of anaesthesia

authors： Stokes DN,Robson N,Hutton P

更新日期：1989-02-01 00:00:00

abstract：:Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane...

journal_title：British journal of anaesthesia

authors： Wierda JM,Maestrone E,Bencini AF,Boyer A,Rashkovsky OM,Lip H,Karliczek R,Ket JM,Agoston S

更新日期：1989-02-01 00:00:00

abstract：:Moderate to severe arterial oxygen desaturation (SaO2 75-88%) occurred in three of four patients who were given sedation during regional conduction block without the administration of oxygen. No desaturation occurred in six patients given oxygen 2 litre min-1 via a nasal catheter during similar procedures. It is concl...

journal_title：British journal of anaesthesia

authors： Smith DC,Crul JF

更新日期：1989-02-01 00:00:00

abstract：:The kinetics of morphine were studied during balanced anaesthesia in 10 patients undergoing lower abdominal or body surface surgery, and compared with those obtained in nine awake patients receiving morphine i.v. for the relief of chronic non-cancer pain. All patients received morphine sulfphate pentahydrate 10 mg i.v...

journal_title：British journal of anaesthesia

authors： Sear JW,Hand CW,Moore RA,McQuay HJ

更新日期：1989-01-01 00:00:00

abstract：:Gas injection systems used in several techniques of ventilation cause increases in airway pressure and physiological changes which are frequently overlooked. The momentum flux theory describes such phenomena most appropriately. We have defined and measured the characteristics of such increases in airway pressure, usin...

journal_title：British journal of anaesthesia

authors： Isabey D,Boussignac G,Harf A

更新日期：1989-01-01 00:00:00

abstract：:A new method has been developed to measure end-tidal carbon dioxide partial pressure (PECO2) during high frequency jet ventilation (HFJV). A digital flow controller incorporated in a computerized high frequency jet ventilator was used to deliver either a single deep breath or a series of three deep breaths. On user re...

journal_title：British journal of anaesthesia

authors： Sehati S,Young JD,Sykes MK,McLeod CN

更新日期：1989-01-01 00:00:00

abstract：:Hypertensive patients were monitored for myocardial ischaemia during anaesthesia and surgery with the V5 lead of a standard electrocardiograph. Myocardial ischaemia was detected in 11 of 39 untreated hypertensive patients and in four of seven receiving therapy with a diuretic, but in none of 44 receiving atenolol. Fou...

journal_title：British journal of anaesthesia

authors： Stone JG,Foëx P,Sear JW,Johnson LL,Khambatta HJ,Triner L

更新日期：1988-12-01 00:00:00